Regimen Lab Skincare Encyclopedia ?

Genistein

*Preliminary Lab Notes* - Full Entry Under Development

Ingredient Profile

Common Name: Genistein
INCI: Genistein
Source: Soybeans, Fava beans
Genistein Molecule

kligman ingredient evaluation

Penetration: Under analysis
Biochemical Mechanism: Under analysis
Level of Evidence: Under analysis

What is Genistein?
Genistein is an isoflavone used in skincare products to improve skin dryness and wrinkles.
Source?
Genistein is derived from soy


https://pubchem.ncbi.nlm.nih.gov/compound/5280961

what it is, source, how it works (specific radical species it targets), other benefits, clinical trials with concentration, in vivo or in vitro tests, does it penetrate, scientific consensus on effectiveness,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312494/
https://academic.oup.com/jn/article/133/11/3811S/4818027 https://academic.oup.com/carcin/article/27/8/1627/2476206



How it works?

Other benefits?
Skin elasticity, photoaging and skin cancer prevention.

Clinical trials
https://www.tandfonline.com/doi/full/10.1080/09513590.2017.1320708?scroll=top&needAccess=true - Collagen concentration on the facial skin of postmenopausal women after topical treatment with estradiol and genistein: a randomized double-blind controlled trial.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936027/ - Genistein aglycone improves skin repair in an incisional model of wound healing: a comparison with raloxifene and oestradiol in ovariectomized rats.

?
The Skincare Encyclopedia aims to improve public understanding of the biology and chemistry of skincare. The Encyclopedia is rooted in core scientific principles and extensive research, in many cases in collaboration with the authors of the original studies referenced. This is a project of Regimen Lab, maintained by a group of multidisciplinary scientists, MDs, and researchers.

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