Regimen Lab Skincare Encyclopedia ?

Saccharide Isomerate

*Preliminary Lab Notes* - Full Entry Under Development

Ingredient Profile

Common Name: Saccharide Isomerate
INCI: Saccharide Isomerate
Source: Synthesized through Biotechnology

kligman ingredient evaluation

Penetration: Under analysis
Biochemical Mechanism: Under analysis
Level of Evidence: Under analysis

Regimen's Take

Saccharide Isomerate is a humectant that promotes water retention and improves desquamation (the sloughing of dead skin cells). The body naturally sheds old skin cells as it regenerates, but if your skin is dehydrated, this process is halted as your skin retains the cells in order for added protection. This results in the feeling and appearance of rough skin. While this is great for dehydration / dry skin, Saccharide Isomerate is particularly helpful to avoid dry/flaky skin, for example as the winter approaches. Structurally similar to Natural Moisturizing Factors Saccharide Isomerate upregulates skin processes that produce HA and


Look for Saccharide Isomerate in combination with glycerin, as the combination of the two has been studied extensively and shows that they promote healthy desquamation.
Saccharide Isomerate
The Skincare Encyclopedia aims to improve public understanding of the biology and chemistry of skincare. The Encyclopedia is rooted in core scientific principles and extensive research, in many cases in collaboration with the authors of the original studies referenced. This is a project of Regimen Lab, maintained by a group of multidisciplinary scientists, MDs, and researchers.