Regimen Lab Skincare Encyclopedia ?
Pentacyclic Triterpenes of Centella asiatica
*Preliminary Lab Notes* - Full Entry Under Development
Ingredient Profile |
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Common Name: Pentacyclic Triterpenes of Centella asiatica |
INCI: Pentacyclic Triterpenes of Centella asiatica |
Source: Centella Asiatica |
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kligman ingredient evaluation |
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Penetration: Under analysis |
Biochemical Mechanism: Under analysis |
Level of Evidence: Under analysis |
Regimen's Take
Also known as TECA (Triterpenes extracted from Centella Asiatica, [Gotu Kola]). Gotu Kola has long been known for anti-inflammatory and moisturizing properties. High amount of triterpenoid sapononines, terpenes tend to have a great effect on the body. Main terpenoids: asiatic acid, asiticoside, madecassic acid and madecassoside. Also includes a number of flavonoids - which are strong antioxidants. Also contains phenolic compounds, which tend to be good anti-aging and anti-inflammatories. TECA is FDA-approved when used in over-the-counter skin repair products for wound healing, collagen repair, boosting vital proteins within the dermis, etc. The strong clinical studies behind TECA's components mean in skincare products, TECA has moisturizing, barrier support, and anti-aging properties (e.g. reduces appearance of stretch marks). We recommend TECA for those of all skin types and concerns. Its anti-inflammatory properties can help reduce signs of aging in the long term Skin Repair Moisture Barrier Anti-Aging
TLDR
Clinical studies have only shown benefit starting at .2% and potentially up to 1%, so look for TECA in these concentrations.
These studies also look at the use of TECA 2-4 times a day, so consider using it at least twice a day.
One study showed reduction of post-natal stretch marks reduced by 40% and discoloration by 50% compared to reductions of 3%-6% when using placebo.
Pentacyclic Triterpenes of Centella asiatica / Asiatic Acid
https://pubchem.ncbi.nlm.nih.gov/compound/119034
(ASIATIC ACID)